Identification of functional common and rare variants in the CD40 signaling pathway in Rheumatoid Arthritis
Category
FP7 Project with U.S. partner
Short name and number
CD40RA (237280)
Area
Health
Description
Rheumatoid Arthritis is a common chronic autoimmune disease that affects approximately 1% of the adult population worldwide. Although its causes are largely unknown, it is clear that there is a considerable heritable component. In 2007, three genome-wide association studies (GWAS) as well as candidate gene approaches successfully increased the number of RA gene loci from two to five.
Participating Countries
The Netherlands and United States.
Name of US Partner
PRESIDENT AND FELLOWS OF HARVARD COLLEGE
Contact
ACADEMISCH ZIEKENHUIS LEIDEN - LEIDS UNIVERSITAIR MEDISCH CENTRUM (NL) / VAN DER VOORT Ellen