Single Particle Cryo-Electron Microscopy and Biophysical Characterization of Transient Receptor Potential Vanilloid 2 channel: a Three-Dimensional Structure Characterization of a Membrane Nociceptor.
Category
FP7 Project with U.S. partner
Short name and number
Pain_TRPV2 (237120)
Area
Health
Description
The IOF call is a unique opportunity for the researcher to carry out this project. Transient Receptor Potential channels are extremely interesting since some of them are receptors for pain (nociceptors). The actual subject of research is the structural characterization of TRPV2, a nociceptor which responds to different stimuli such as cannabidiol, pressure and noxious heat. TRPV2 is expected to be a large membrane protein (potential homotetramer of ~400 KDa).
Participating Countries
Spain and United States.
Name of US Partner
The Brigham and Women's Hospital, Inc.
Contact
UNIVERSITAT AUTONOMA DE BARCELONA (ES) / GONZALEZ MATOS Queralt