Alpha-Catenin regulatory properties and functions during Zebrafish development.
Category
FP7 Project with U.S. partner
Short name and number
Alpha-Catenin roles (236027)
Area
No theme specific
Description
Adherens junctions (AJ) play key roles in cell-cell adhesion, cell migration and cell signaling in a variety of biological processes. AJ are dynamic structures composed of cell-cell adhesion proteins (cadherin super-family), associated adaptor proteins (alpha-, and beta-catenin) and other proteins (p120) that locally regulate the actin cytoskeleton. The functions of two components of the AJ, cadherins and beta-catenin, are well understood, but the function of alpha-catenin is not.
Participating Countries
Germany and United States.
Name of US Partner
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
Contact
EUROPEAN MOLECULAR BIOLOGY LABORATORY (DE) / REINKE Genevieve