The SRA domain: a connection between DNA methylation and histone modifications within the epigenetic code? The Arabidopsis VIM family.
Category
FP7 Project with U.S. partner
Short name and number
SRA AND EPIGENETICS (234849)
Area
Health
Description
Heterochromatin in both mammals and plants is associated with methylation of cytosines within the DNA sequence. While DNA methylation is widespread in plants, fungi, and animals, it has been curiously lost in Saccharomyces cerevisiae, Schizosaccharomyces pombe, Caenorhabditis elegans, and Drosophila. However, the methylation system in Arabidopsis is very similar to that in mammals, showing that DNA methylation is highly conserved, and that Arabidopsis is an excellent model system to study it.
Participating Countries
Spain and United States.
Name of US Partner
UNIVERSITY OF CALIFORNIA, LOS ANGELES
Contact
AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) / ABAD RUIZ Carlos Manuel